Portal Instruments is focused on needle-free drug delivery and solving the challenge of self-administering biological medicines. Portal’s platform is in development and not available for sale or use.

We are developing a highly innovative needle-free jet injection platform licensed from MIT, that transforms the drug delivery experience for patients suffering from chronic disease. Our aim is to replace all needles and syringes with a safe, fast, and connected device and to become the standard for modern drug delivery.



Portal Instruments needle free device

At Portal we believe that patients deserve more than a 160 year old technology, the needle & syringe

no needle graphic

Our Vision is a Needle Free World

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Our Mission is to improve the experience for patients on life-changing therapies



  • We are patient-centric and everything we do focuses around improving the patient experience and outcome
  • We partner with pharma companies to improve and enable their life-changing therapies and are the easiest, smartest company to partner with
  • We bring to market innovative, creative, and disruptive ideas in the field of drug delivery
  • We hold ourselves to the highest standards of honesty, integrity, and intellectual rigor
  • We realize that it will take an amazing and diverse team to fulfill our mission and value teamwork, collegiality, transparency and inclusion
  • We can only expand our organization by continuously teaching and growing our people
  • We are relentless about finding clear solutions to real problems efficiently
  • We are results-driven and will do what it takes to get it done


To build a needle-free drug delivery system that is transformative, interactive, and easy to use, and to go to market with pharmaceutical partners who develop life-changing biologics and biosimilars that treat chronic diseases.



Portal has assembled a team of passionate leaders from the medical device industry bringing together their collective experiences of medical device development and commercialization.

Sanofi is dedicated to supporting people through their health challenges. Sanofi is a global biopharmaceutical company focused on human health. Sanofi prevents illness with vaccines and provides innovative treatments to fight pain and ease suffering. Sanofi stands by the few who suffer from rare diseases and the millions with long-term chronic conditions. With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe.

5AM Ventures is a leading venture capital firm focused on building next-generation life science companies capable of delivering outstanding returns to our investors. 5AM’s investment professionals possess strong scientific, medical, operational, legal and finance expertise.

Takeda Pharmaceutical Company Limited is a global, research and development-driven pharmaceutical company committed to bringing better health and a brighter future to patients by translating science into life-changing medicines. Takeda focuses its R&D efforts on oncology, gastroenterology and central nervous system therapeutic areas plus vaccines. Takeda conducts R&D both internally and with partners to stay at the leading edge of innovation. New innovative products, especially in oncology and gastroenterology, as well as our presence in Emerging Markets, fuel the growth of Takeda. More than 30,000 Takeda employees are committed to improving quality of life for patients, and working with partners in health care in more than 70 countries. For more information, visit https://www.takeda.com

Gerresheimer AG is the global go-to partner for medicine packaging, drug delivery devices and solutions with the broadest product range for pharma, health, well-being and biotech. They bring every kind of medicine safely, reliably and conveniently to or into the patient. Customers and partners from all over the world approach them with new challenges. They are their solution provider with the absolute will to deliver, from the concept up to the final product. This is how Gerresheimer meets the needs of our customers and their customers – the users. For more information visit https://www.gerresheimer.com/en/company/about-us

Portal Instruments team photo with needle free device

Pages of the Portal Instruments website may contain links to third party websites that are not under the control of Portal Instruments. Portal Instruments is not responsible for the content of any such site and the inclusion of these links does not imply the endorsement of the content of the linked site by Portal Instruments.

Portal’s platform is in development and not available for sale or use.